Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine

What to know

The ATSDR Interaction Profile succinctly characterizes the toxicologic and adverse health effects information for mixtures of hazardous substances. Each profile identifies and reviews key literature that describes toxicologic properties of featured mixtures. This profile provides information on the mixture of Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine.

Final Interaction Profile: August 2006

CAS#:

  • Atrazine 1912-24-9
  • Deethylatrazine 6190-65-4
  • Diazinon 333-41-5
  • Nitrate 14797-55-8
  • Simazine 122-34-9

Complete Profile

Preface

  • Summary
  • Contributors
  • Peer review
  • Contents
  • List of figures
  • List of tables
  • List of acronyms, abbreviations, and symbols

Introduction

Joint Toxic Action Data for the Mixture of Concern and Component Mixtures

  • 2.1 Mixture of Concern
  • 2.2 Component Mixtures
  • 2.3 Relevance of the Joint Toxic Action Data and Approaches to Public Health
  • 2.4 Recommendations for Data Needs

Recommendations for Exposure-Based Assessment of Joint Toxic Action of the Mixture

Conclusions

List of References

Appendices

  • A. Background Information for Atrazine and Deethylatrazine
  • B. Background Information for Simazine
  • C. Background Information for Diazinon
  • D. Background Information for Nitrate
  • E. Chemical Structures of Organic Mixture Components

Peer-review comments on the Interaction Profile for Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine

Responses to peer-review comments on the Interaction Profile for Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine

EPA comments on the Interaction Profile for Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine

Responses to EPA comments on the Interaction Profile for Atrazine, Deethylatrazine, Diazinon, Nitrate, and Simazine

Public comments from CRE (Center for Regulatory Effectiveness)

Public comments from CTRAPS (Consultants in Toxicology, Risk Assessment, and Product Safety)

Public comments from Syngenta

Responses to public comments

Request for Correction of ATSDR Mixtures Guidance Document

Response to Request for Correction of ATSDR Mixtures Guidance Document

Reference

Agency for Toxic Substances and Disease Registry (ATSDR). 2004. Interaction profile for atrazine, deethylatrazine, diazinon, nitrate, and simazine. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.

Accessing Interaction Profile PDFs

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