Framework: Assessing Health Impacts of Multiple Chemicals

What to know

This framework document describes a recommended process. It is used to evaluate potential public health impacts of exposures to multiple chemicals.

Framework for Assessing Health Impacts of Multiple Chemicals

Complete Manual

Preface

  • Summary
  • Contributors
  • Peer review
  • Contents
  • List of figures
  • List of tables
  • List of acronyms, abbreviations, and symbols
  • Executive Summary

Introduction

ATSDR Approach

Options and Issues for Assessing Health Impacts of Exposures to Multiple Chemicals and Other Stressors

References

Appendices

  • A. Background Information on the assessment of additivity and interactions
  • B. Weight-of-Evidence methods
  • C. Methods used or proposed by other agencies

Reference

Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Framework for Assessing Health Impacts of Multiple Chemicals and Other Stressors. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.

Accessing Interaction Profile PDFs

To access PDF files for the interaction profiles, use Adobe Acrobat Reader by clicking this link: Adobe.