1,4-Dioxane

Academic and Professional Credentials:

• Ph.D. in Pharmacology and Toxicology, University of California at Davis
• B.A. in Chemistry, Swarthmore College, Swarthmore, PA
• DABT

Current Position Title:

Deputy Director for Scientific Affairs, Office of Environmental Health Hazard Assessment

Organizational Affiliation(s)

California Environmental Protection Agency

Areas of Expertise, Discipline, Relevant Experiences

Dr. Alexeeff oversees a staff of over 80 scientists (including physicians, toxicologists, and epidemiologists) in multidisciplinary evaluations of the health impact of pollutants and toxicants in air, water, soil and other media. Areas include: identification of carcinogens and reproductive toxins in the environment, through the evaluation of human and animal data as well as indicators of special susceptibility; review of epidemiological and toxicological data to identify hazards and derive risk-based assessments; development of guidelines to identify chemicals hazardous to the public and compounds to which infants and children may have increased susceptibility; recommending ambient air quality standards for California; identifying toxic air contaminants; characterizing air toxics hot spots; developing public health goals for contaminants in water; preparing Proposition 65 evaluations for carcinogens and developmental/reproductive toxins; issuing sport fish consumption advisories to the public; conducting epidemiological studies or investigations, developing indicators of environmental quality; pesticide poisoning illness surveillance, training health personnel on pesticide poisoning recognition; reviewing hazardous waste site risk assessments; and conducting multi-media risk assessments. He has reviewed over 140 documents evaluating human epidemiological or animal toxicological evidence for the Office of Environmental Health Hazard Assessment or other agencies such as U.S. EPA. Dr. Alexeeff is also an Associate Adjunct Professor in the Department of Environmental Toxicology at the University of California, Davis.

Recommended by Scientific/Professional Society or General Public

Academic and Professional Credentials:

Ph.D., M.S., Pharmacology/Toxicology, Purdue University
B.S., Chemistry, University of California, Davis
DABT

Current Position Title:

Consultant in toxicology

Organizational Affiliation(s)

• Member, American Board of Toxicology
• Society of Toxicology and its regional chapter
• International Society of Regulatory Toxicology/Pharmacology
• American Chemical Society and its regional chapter

Areas of Expertise, Discipline, Relevant Experiences

Dr. Leber has been a toxicology consultant since 1988, in which capacity he has served, most recently, as senior toxicologist and project manager for Goodyear Tire and Rubber. Dr. Leber is an expert in the toxicology of volatile organics and pesticides. Dr. Leber has assisted in the development and expert review of EPA Drinking Water Advisories. He has performed health assessments for chemicals found in environmental settings (air, water, soil), underground tanks, and in the workplace; calculated chemical levels deemed safe for various exposure media; provided toxicological expertise and comments addressing development of Indoor Air Quality (IAQ) standards under consideration by OSHA. He has also participated in assessment of IAQ in residential and occupational-setting projects. Dr. Leber assisted law firms in approximately 20 cases as an expert witness in toxic tort actions involving alleged personal injuries from chemical agents (pesticides, solvents, corrosives, heavy metals, combustion products) found in occupational and non-occupational environments. Issues in these cases included cancer causation, lung, eye, and dermal injuries, and neurological and kidney lesions. He has authored and coauthored dozens of scientific journal articles and book chapters, and has given over 25 invited lectures to scientific groups and symposia all over the world. Dr. Leber has peer reviewed ATSDR’s toxicological profiles on nickel, pentachlorophenol, phosgene, 1,4-dioxane, 3,3-dichlorobenzidine, benzene, chlordane, ethylene glycol and propylene glycol, and ethylene oxide.

Recommended by Scientific/Professional Society or General Public

Academic and Professional Credentials:

• Post Doctoral Fellow, University of Minnesota
• Ph.D. (Pharmacology), Minor Biochemistry, University of Minnesota
• D.V.M. (B.V.Sc.), University of Rajasthan, India
• Certified Industrial Hygienist
• ABT
• DABVT

Current Position Title:

Fred C. Davison Distinguished Chair in Toxicology, College of Veterinary Medicine, Department of Physiology and Pharmacology, University of Georgia, Athens

Organizational Affiliation(s)

• Fellow of American College of Veterinary Toxicologists
• Member, Society of Toxicology
• American Society for Pharmacology and Experimental Therapeutics
• American Veterinary Medical Association
• American Association for the Advancement of Science
• New York Academy of Sciences
• International Society for Biochemical Pharmacology
• Society for Geochemistry and Health
• The Society of Sigma Xi
• American Industrial Hygiene Association
• American Academy of Industrial Hygiene
• Phi Zeta, the National Honor Society

Areas of Expertise, Discipline, Relevant Experiences

Dr. Sharma is one of the foremost pharmacological and environmental toxicologists in the U.S. His current duties include research in toxicology, in which his primary areas of interest are pesticides and the health effects of environmental pollutants, and teaching professional veterinary students and graduate students. He is also Graduate Coordinator of the interdisciplinary graduate program in toxicology.

Dr. Sharma has been on the editorial board of several professional journals, including: Fundamental and Applied Toxicology; Environmental Toxicology and Chemistry; Journal of Environmental Pathology and Toxicology; Toxicology and Industrial Health; and is currently on the board of the European Journal of Pharmacology (Environmental Toxicology and Pharmacology Section); and Environmental Toxicology and Pharmacology; and is assistant editor for Poisindex.

He has also peer reviewed articles and submissions for over a dozen professional scientific journals, including; Toxicology and Applied Pharmacology; Pesticide Biochemistry and Physiology; Toxicological Sciences; Journal of Agricultural and Food Chemistry; International Immunopharmacology; Biomedical and Environmental Sciences; Archives of Environmental Contamination and Toxicology; and the European Journal of Pharmacology. He has edited 4 seminal books, two on immunological toxicology, one on mycotoxins and phytoalexins and one titled “Dietary Factors and Birth Defects,” has authored and coauthored over 40 chapters in scientific books, and published over 260 research articles in scientific journals. Dr. Aharma has served as a peer reviewer for ATSDR’s toxicological profiles on 1,4-dioxane, aldrin/dieldrin, fluorides, fluorine, hexachlorocyclohexanes, hydrazines, hydrogen fluoride (MMG), selenium, and tungsten.

Recommended by Scientific/Professional Society or General Public